Palmitoyl Pentapeptide-4

Introduction:

English alias: Matrixyl (PAL-KTTKS); Pal-Lys-Thr-Thr-Lys-Ser-OH; N2-(1-Oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine; Palmitoyl Pentapeptide PAL-Lys-Thr-Thr-Lys-Ser; PalMitoyl Pentapeptide-4

English name: Palmitoyl Pentapeptide-4

Appearance: white powder

Content: ≥99% (HPLC)

Chemical formula: C39H75N7O10

CAS No.: 214047-00-4

Molecular weight: 802.05

Density: 1.147 g/cm3(Predicted)

Acidity coefficient (pKa): 2.98±0.10(Predicted)

Storage conditions: -20℃, valid for 2 years, please use within one month after dissolving in solvent at -20℃.

Beauty pentapeptide is also a kind of beauty peptide. The prototype of the peptide is palmitic acid pentapeptide, commonly known as pentapeptide, which can simulate the paralysis effect of botulinum toxin. It is a short peptide fragment formed by peptide bonds of five amino acids. The structure is similar to protein, but the peptide chain of protein is longer, usually composed of hundreds of amino acids. These peptides can be divided into dipeptides (containing two amino acids), tripeptides (containing three amino acids), tetrapeptides (containing four amino acids), etc. according to the number of amino acids they contain. Due to the different varieties of amino acids contained, dipeptides also have different varieties, and so do tripeptides; at the same time, with the same few amino acids, the order (link) of each amino acid is different, and dipeptides will also have different varieties. So there are now various functions and various names of peptides. Pentapeptide is composed of six amino acids (Pal-palmitic acid, Lys-lysine, Thr-threonine, Thr-threonine, Lys-lysine, Ser-serine).

Palmitoyl Pentapeptide-4 is a very popular anti-aging active ingredient belonging to the pentapeptide class and is often used in skin care products. It is a short peptide composed of five amino acids, which improves its permeability in the skin by binding to palmitic acid.

The effects and benefits are as follows:

Promote collagen synthesis: Palmitoyl Pentapeptide-4 can stimulate fibroblasts in the skin to synthesize collagen, elastin and glycosaminoglycans, which helps improve the elasticity and firmness of the skin and slow down the aging process of the skin.

Reduce fine lines and wrinkles: Because it can promote the production of collagen, Palmitoyl Pentapeptide-4 can effectively reduce the appearance of fine lines and wrinkles, especially deep wrinkles. It has a repairing effect on existing wrinkles and makes the skin smoother.

Enhance skin barrier function: By promoting the synthesis of matrix proteins, it can enhance the function of the skin barrier, make the skin healthier, and reduce the damage of external harmful substances to the skin.

Improve skin texture: Long-term use of palmitoyl pentapeptide-4 products can significantly improve skin texture, make the skin softer and smoother, and brighten the skin tone.

Gentle and non-irritating: Compared with some other powerful anti-aging ingredients, such as retinol, palmitoyl pentapeptide-4 is less irritating and suitable for sensitive skin.

Due to its multiple anti-aging effects and good tolerance, palmitoyl pentapeptide-4 is widely used in skin care products such as anti-wrinkle essences, face creams and eye creams, and is regarded as a safe alternative to "botulinum toxin".

Main uses

As one of the earliest signal peptides used in skin care products, palmitoyl pentapeptide has a clear anti-aging effect. It can effectively improve skin roughness, reduce the number of fine lines, reduce the depth and area of wrinkles, etc., and has the characteristics of being mild and non-irritating. There are a lot of basic research and literature to prove its efficacy.

1. Palmitoyl pentapeptide-4 can penetrate the dermis to increase collagen and reverse the aging process of the skin by rebuilding from the inside out.

2. Palmitoyl pentapeptide-4 is actually the C-terminal fragment of collagen I, which has similar effects to laser surgery.

3. It stimulates the proliferation of collagen, elastic fibers and hyaluronic acid, increases the water content and water retention of the skin, increases skin thickness and reduces fine lines.

4. It can increase the absorption effect.

5. The amount added in cosmetics is 0.01%.