Undecylenoyl Phenylalanine

Introduction:

English name: Undecylenylphenylalanine

English alias: acylamidin; N-(1-oxo-10-undecenyl)-L-phenylalanine; phenylalanine undecenone

Appearance: white powder

Relative molecular weight: 331.45

CAS RN: 175357-18-3

EINECS number: 446-800-7

Molecular formula: C20H29NO3

Melting point: 109 to 112 ℃

Density: 1.047±0.06 g/cm3

Solubility: easily soluble in esters.

Content: ≥99% (HPLC)

Undecylenoylphenylalanine, also known as acylbenzamine, is a melanin stimulating hormone (α-MSH) receptor antagonist. It acts on the biochemical reactions at various stages of melanin formation caused by α-MSH, intercepts melanin production signals, controls the binding of α-MSH (melanocyte stimulating hormone) and melanin production factors, effectively inhibits the activity of tyrosinase, and thus inhibits the formation of melanin. It is mainly used in cosmetics as a whitening agent.

Main effects

(1) Acylbenzamine can effectively inhibit the formation of melanin caused by α-MSH, and can also act on multiple stages of melanin formation. It is used to whiten or reduce the deposition of epidermal melanin, improve skin problems such as dullness and roughness, even out skin color, and prevent, delay and treat excessive pigmentation in the skin (such as excessive pigmentation after inflammation, spots such as age spots, etc.).

(2) Acylamidin can combine with niacinamide. Acylamidin can prevent melanin synthesis from the source (i.e. inhibit melanin production signals and inhibit melanin production enzyme activity), while niacinamide interferes with the melanin synthesis pathway (i.e. inhibit melanin transport to the stratum corneum and accelerate melanin stratum corneum metabolism). They work together to achieve whitening and spot-removing effects. It can be used to prepare stable, non-discoloring lotions, creams, transparent aqueous solutions or gels, etc.