
Introduction
Name: Azithromycin
C.A.S NO. : 83905-01-5
Assay (%)(HPLC, Basis on drying):99%
Molecular formula: C38H72N2O12
Molecular weight : 748.98
Characteristic: White crystalline powder
Melting point: 113-115°C
Solubility: Almost insoluble in water, soluble in anhydrous ethanol and dichloromethane.
Application :
1.Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear i nfections, strep throat, pneumonia, typhoid, and sinusitis;
2.It has been used primarily to prevent bacterial infections in infants and those with weaker immune system3.It is also effective against certain sexually transmitted infections,
such as non- gonococcal urethritis, chlamydia, and cervicitis;
4.Azithromycin is used for acute pharyngitis, acute tonsillitis caused by Streptococcus pyogenes;
5.Azithromycin is used for acute throat and tonsillitis which are caused by streptococcus pyogenes, otitis;
6.Azithromycin can treatment of media sinusitis acute bronchitis skin soft tissue infection which are caused by sensitive bacteria;
7.Azithromycin is also used for pneumonia urethritis cervicitis and so on.
| ITEMS | SPECIFICATIONS | RESULTS |
| Appearance | A White or almost white crystalline powder | Conforms |
| Solubility | Practically insoluble in water,freely soluble in anhydrous ethanol and in methylene chloride | Conforms |
| Identification | IR | Conforms |
| HPLC | ||
| Crystallinity | Meet the requirements | Conforms |
| PH | 9.0 ~ 11.0 | 9.9 |
| Related substances | Desosaminylazithromycin ≤0.3% | DL |
| N-demethylazithromycin ≤0.7% | 0.001 | |
| Any other single impurity ≤1.0% | Conforms | |
| Total impurities≤3.0 % | 0.015 | |
| Residual solvents | Acetone ≤0.5% | 0.003 |
| Loss on drying | 4.0 % ~ 5.0% | 0.045 |
| Residue on Ignition | ≤0.3% | 0.0004 |
| Melting point | 50 °C ~ 60 °C | 50 °C ~ 60 °C |
| Sulphate ash | ≤0.1% | 0.0005 |
| Heavy metals | ≤ 25 ppm | NMT25 ppm |
| Assay ( calculated on the anhydrous basis) | 945 ug ~ 103 ug of azithromycin per mg | 982 ug/ mg |
Service Hotline:
+8618092446649Business Cooperation:
lily@tnjone.comTalent Recruitment:
lily@tnjone.com