
Gentamicin hydrochloride is a broad-spectrum antibiotic belonging to the aminoglycoside class of drugs. It is mainly used in veterinary medicine and is widely used to treat bacterial infections in animals. It is effective against a variety of Gram-negative bacteria and some Gram-positive bacteria, and is commonly used in animals such as pigs, cattle, sheep, horses, dogs and cats.
Melting point: 194°C
Storage conditions: Inert atmosphere, 2-8°C
Solubility: H2O: 50 mg/mL, clear, light yellow
1. Pharmacological action
Gentamicin hydrochloride has a strong antibacterial effect by inhibiting bacterial protein synthesis and interfering with bacterial growth and reproduction.
It is effective against some Gram-negative bacteria (such as Escherichia coli, Salmonella, Pseudomonas) and some Gram-positive bacteria (such as Staphylococcus aureus and Streptococcus).
2. Indications
Respiratory tract infections: used to treat respiratory tract infections such as pneumonia and tracheitis caused by bacteria.
Urinary tract infection: Effective treatment of bacterial infections of the urinary system, such as pyelonephritis, cystitis, etc.
Skin and soft tissue infections: Suitable for skin infections, wound infections and abscesses, etc.
Gastrointestinal infections: Can be used to treat gastrointestinal infections caused by bacteria.
3. Administration
Spectinomycin hydrochloride is usually administered by injection, oral administration or drinking water, and the specific usage needs to be adjusted according to the advice of the veterinarian.
The dosage and course of treatment should be reasonably calculated according to the type, weight and condition of the animal.
4. Precautions
Allergic reactions: Some animals may be allergic to aminoglycosides, and the health status of the animal should be confirmed before use.
Renal toxicity: Long-term use or high-dose use may be toxic to the kidneys, and the renal function of the animal should be monitored.
Withdrawal period: In animals using spectinomycin hydrochloride, the prescribed withdrawal period must be followed to avoid drug residues from affecting human health.