
Introduction:
English alias: 4-Hydroquinone-alpha-D-glucopyranoside; a-Arbutin
Chinese name: alpha-arbutin
Chinese alias: alpha-arbutin; 4-hydroquinone-alpha-D-pyranoglucoside; hydroquinone-alpha-D-glucoside; α-arbutin; 4-hydroxyphenyl-α-D-pyranoglucoside
Relative molecular weight: 272
CAS RN: 84380-01-8
Melting point: 203~ 207±1℃
Content: ≥99% (HPLC)
α-arbutin, also known as alpha-arbutin, is a chemical substance that can be used in cosmetics as a whitening agent. Arbutin is a hydroquinone glycoside compound with the chemical name of 4-Hydroquinone-alpha-D-glucopyranoside. It exists in plants such as bearberry and bilberry. It is an emerging natural whitening active substance that is non-irritating, non-allergic and highly compatible. There are two structural and functional functional groups in the molecular structure of arbutin: one is glucose residue; the other is phenolic hydroxyl group. α-Arbutin is physically white to light gray powder and is more soluble in water and ethanol.
Efficacy
α-Arbutin has a good therapeutic effect on scars caused by ultraviolet burns, and has good anti-inflammatory, repair and whitening effects. It can inhibit the production and deposition of melanin and remove spots and freckles.
Mechanism of action
The whitening mechanism of α-Arbutin directly inhibits the activity of tyrosinase, thereby reducing the production of melanin, rather than reducing the production of melanin by inhibiting cell growth or tyrosinase gene expression. Since α-arbutin is a more efficient and safer whitening active substance, many cosmetic companies at home and abroad have adopted α-arbutin instead of β-arbutin as a whitening additive.
Application
Alpha-arbutin is a chemical substance. Alpha-arbutin is similar to arbutin and can inhibit the production and deposition of melanin, remove spots and freckles. Studies have shown that α-arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than arbutin. Alpha-arbutin can be used as a whitening agent in cosmetics.
Uses
Alpha-arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than arbutin
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